Tetraphase Pharmaceuticals (Watertown, MA) a clinical-stage biopharmaceutical company focused on broad spectrum antibiotics for the treatment of gram negative pathogens, unrinary tract infections and community acquired bacterial pneumonia, closed a $45M Series C financing. Participants include Excel Venture Management, CMEA Capital, Fidelity Biosciences, Flagship Ventures, Mediphase Venture Partners and Skyline Ventures.