CeNeRx (Cary, NC) a clinical-stage biopharmaceutical company focused on diseases of the central nervous system, closed a $10M Series C, bringing the round total to $14M. Participants include Aisling Capital, L Capital Partners and Pappas Ventures.

Liquidia Technologies (Research Triangle Park, NC) a development-stage company focused on improving delivery of inhaled therapeutics and vaccines via nanoparticles with optimized characteristics for increased target specificity, closed a $5M Series C financing, bringing the total round to $25M. Participants include Canaan Partners, Pappas Ventures, New Enterprise Associates, Morningside, Firelake Capital and PPD

TearScience (Morrisville, NC) a clinical-stage medical device company focused on the treatment of chronic evaporative dry eye due to obstructive Meibomian Gland Dysfunction, closed a $44.5M Series C financing. Participants include Essex Woodlands Health Ventures, Investor Growth Capital, General Catalyst, De Novo Ventures, Spray Ventures and Quaker Bio Ventures.

Liquidia (Morrisville, NC) a development-stage company focused on improving delivery of inhaled therapeutics and vaccines via nanoparticles with optimized characteristics for increased target specificity, closed a $13M Series C financing, bringing the total round to $20M. Participants include Canaan Partners, Pappas Ventures, New Enterprise Associates, Morningside and Firelake Capital.

TheraSim (Durham, NC) a commercial-stage medical technology company focused on a suite of clinical performance management tools, closed a $1.2M Series A financing. Participants include Andromeda Capital.

PhaseBio Pharmaceuticals (Research Triangle Park, NC) a development-stage biopharma company focused on elastin-like fusion proteins for improved expression and purification of biological, closed a $25M Series B financing. Participants include New Enterprise Associates, Hatteras Venture Partners, Johnson & Johnson Development Corp. and Fletcher Spaght Ventures.

TransEnterix (Durham, NC) a development-stage medical device company focused on a laparoscopic surgical platform for minimally invasive abdominal surgeries, closed a $55M Series B financing. Participants include Aisling Capital, Intersouth Partners, Quaker BioVentures, SV Life Science Advisers, Synergy Life Science Partners and Parish Capital Advisors.
Note: 2009 Year-in-Review Trend Analysis Coming 15 Feb

Centice (Morrisville, NC) developer of a pharmaceutical verification device to improve accuracy of dispensed medications, closed a $6.1M Series C financing. Participants include Fulcrum Financial Group, The Aurora Funds, S-Group Direct Investments, Innovation Ventures and Novak Biddle Venture Partners.
Note: 2009 Year-in-Review Trend Analysis Coming 15 Feb.

Metabolon (Durham, NC) a metabolomics services and informatics company focused on detection of small molecule biomarkers, closed a $6M Series C financing, bringing the entire financing round to $12.3M. Participants include Syngenta Ventures, Fletcher Spaght Ventures, Sevin Rosen Funds, Aurora Funds, Harris and Harris Group, Fulcrum Financial Partners and Alexandria Equities.

Micell Technologies (Raleigh, NC) a development-stage medical device company focused on a fluid-based drug eluting stents for the interventional cardiology market, closed a $15M Series B financing. Participants to date have included St.Jude Medical, Invemed Catalyst Fund and GE.