Great Lakes Pharmaceuticals (Cleveland, OH) a clinical-stage drug:device company focused on catheter-related bloodstream infection, closed a $3.1M Series B financing. Participants include Charter Life Sciences, Early Stage Partners, Ohio Tech Angels and North Coast Angel Fund.

Swift Biosciences (Ann Arbor, MI) a development-stage company focused on molecular biology reagents for R&D and diagnostics, closed a $3M Series A financing. Participants include DFJ Mercury.

Coskata (Warrenville, IL) a development-stage bacterial fermentation biofuels company closed a $23.7M Series D financing. Participants include Total, Blackstone Group, Advanced Technology Ventures, Globespan Capital Partners, General Motors, GreatPoint Ventures and Khosla Ventures.

Delphinus Medical Technologies (Detroit, MI) a development-stage medical device company focused on tomographic ultrasound imaging for breast cancer, closed an $8M Series A financing. Participants include Arboretum Ventures, Beringea and North Coast Technology Investors.

Virent Energy Systems (Madison, WI) a development-stage biofuels company focused on catalytically transforming soluble biomass into hydrocarbons, closed a $46.4M Series C financing. Participants include Shell and Cargill Ventures.

Anulex Technologies (Minnetonka, MN) a commercial-stage medical device company focused on herniated discectomy procedures, closed a $18.3M Series E financing. Participants include Hatteras Late Stage VC Fund, Affinity Capital, Delphi Ventures, MB Venture Partners, New Enterprise Associates, SightLine Partners and Split Rock Partners.

NeuroTherapeutics Pharma (Chicago, IL) a clinical-stage biopharmaceutical company focused on the CNS disorders of epilepsy, acute and neuropathic pain, closed a $43M Series B financing. Participants include Fidelity Biosciences, MPM Capital, S.R. One, Pfizer, Novo Ventures and Thomas McNerney & Partners.

Cellular Dynamics (Madison, WA) a commercial-stage supplier of cardiomyocytes derived from, closed a $40.6M Series B financing. Participants include Tactics II Stem Cell Ventures, Equity Group Investments and Sixth Floor Investors.

Rapid Diagnostek (Hudson, WI) a development-stage medical device company focused on vitro diagnostics using radio frequency phase shift technology for virus detection in fluid samples, closed a $4M Series B financing. Participants include Peak Ridge Capital.

Hemosphere (Eden Prairie, MN) a commercial-stage medical device company focused on vascular access for dialysis patients, closed a $9.3M Series A financing, bringing the total round to $36.3M (GRAFTcath). Participants have included Kaiser Permanente Ventures, Three Arch Partners, Ascension Health Ventures, Affinity Capital Management, Cutlass Capital and Sapient Capital Management.