Advanced Cardiac Therapeutics, Inc.: Series B $5M

Posted in Q - 4Q08, R - MID ATLANTIC, R - NORTH EAST, Uncategorized, X - Anticoagulant, X - Device (Dialysis), X - Device (GI), XX - MI, XX - NH

Advanced Cardiac Therapeutics (Laguna Beach, CA) a development-stage electrophysiology and radiometry medical device company focused on energy delivery via catheters for cardiac ablation, closed a $5M Series b financing. Participants include NBGI Ventures.

Curetis, AG: Series A $1.9M

Posted in I - Series A, Q - 4Q08, R - INTERNATIONAL, X - Device (Diagnostic), X - Tuberculosis

Curetis (Germany) molecular diagnostics company focused on tuberculosis and other severe infectious diseases closed a $1.9M Series A financing. Participants include Aeris Capital.

Prosensa, BV: Series B $25.0M

Posted in I - Series B, Q - 4Q08, R - INTERNATIONAL, X - Muscular Dystrophy, X - RNAi

Prosena (The Netherlands) developer of RNA-based splice modulating therapeutics closed a $25M Series B financing. Participants include GIMV, AGF Management, Abingworth Management, Life Sciences Partnersand MedSciences Capital.

Entra Pharmaceuticals, Inc.: Series A $4.2M

Posted in I - Series A, Q - 4Q08, R - NORTH EAST, XX - MA

Entra Pharmaceuticals (Waltham, MA) a stealthy drug delivery company closed a $4.2M Series A financing. Participants include Flybridge Capital Partners and North Bridge Venture Partners.

CalciMedica, Inc.: Series C $4M

Posted in I - Series C, Q - 4Q08, R - WEST, X - Autoimmune, X - Inflammation, XX - CA

CalciMedica (La Jolla, CA) an early-stage company focused on the calcium release-activated calcium channel is pursuing autoimmune and inflammatory indications, closed a $4M Series C financing. Participants include Biogen Idec, Sanderling Ventures and SR One.

Pioneer Surgical Technology, Inc.: Series B $15

Posted in I - Series B, Q - 4Q08, R - MID WEST, X - Device (Spine), XX - MI

Pioneer Surgical Technology (Marquette, MI) a commercial-stage spinal and orthopedic implant and instrument company closed a $15M Series B financing. Participants include InvestMichigan Growth Capital Fund, Pharos Capital Group, Highlander Partners, Hopewell Ventures and River Cities Capital Funds.

Rcadia Medical Imaging, Ltd. Series B $3.3M

Posted in I - Series B, Q - 4Q08, R - INTERNATIONAL, X - Bioinformatics, X - Cardiology, X - Device (Imaging), X - Imaging

Rcadia Medical Imaging (Israel) developer of image processing based software products for blood vessel analysis closed a $3.3M Series B financing. Participants include BioVentures Investors and 20/20 HealthCare Partners.

ESTECH, Inc.: Series B $11.2M

Posted in I - Series B, Q - 4Q08, R - WEST, X - Device (Cardiology), XX - CA

ESTECH (San Ramon, CA) a commercial-stage developer, manufacturer and distributor of cardiac surgery devices closed a $11.2M Series B financing. Participants include Saints Capital Everest, Telegraph Hill Partners and Waveland Venture Partners.

Seventh Sense Biosystems, Inc.: Series A $4.8M

Posted in I - Series A, Q - 4Q08, R - NORTH EAST, X - TeleMedicine, XX - MA

Seventh Sense Biosystems (Cambridge, MA) a stealthy early-stage health monitoring and telemedicine device company closed a $4.8M Series A financing. Participants include Flagship Ventures, Polaris Venture Partners and Third Rock Ventures.

Semprus BioSciences Corp.: Series A $8M

Posted in I - Series A, Q - 4Q08, R - NORTH EAST, X - Antiinfective, X - Biomaterial, XX - MA

Semprus BioSciences (Cambridge, MA) an early-stage biomaterial surface coating company closed a $8M Series A financing. Participants include 5AM Ventures and Panagea Ventures.

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